QTc Interval (Cardiac Repolarization): Lengthening After Meals
نویسندگان
چکیده
منابع مشابه
Influence of autonomic neuropathy on QTc interval lengthening during hypoglycemia in type 1 diabetes.
Hypoglycemia produces electrocardiographic QTc lengthening, a predictor of arrhythmia risk and sudden death. This results from both sympatho-adrenal activation and a lowered serum potassium. It has been suggested that cardiac autonomic neuropathy (CAN) might indicate those who are at particular risk. We tested this hypothesis in 28 adults with type 1 diabetes and 8 nondiabetic control subjects....
متن کاملMeasurement and regulation of cardiac ventricular repolarization: from the QT interval to repolarization morphology
Ventricular repolarization (VR) is a crucial step in cardiac electrical activity because it corresponds to a recovery period setting the stage for the next heart contraction. Small perturbations of the VR process can predispose an individual to lethal arrhythmias. In this review, I aim to provide an overview of the methods developed to analyse static and dynamic aspects of the VR process when r...
متن کاملKetamine-induced QTc interval prolongation
Sir, Ketamine is a noncompetitive antagonist of the N-methyl-D-aspartate (NMDA) receptor. It is widely used as a dissociative anesthetic and is also used as an adjunct in pain management, particularly in opioid-tolerant patients. It blocks calcium channels and depresses sodium channel function as well as having anticholinergic effects. It inhibits the re-uptake of the catecholamines and may hav...
متن کاملDRUGS AND QTc INTERVAL DISPERSION
The measure of delayed ventricular repolarization most frequently used clinically is the ability of the new chemical entity to prolong the QTc interval on surface electrocardiogram. Intramyocardial dispersion of repolarization appears to play a more important role both in electrical stability of the ventricles and in arrhythmogenesis. The potential importance of myocardial dispersion of refract...
متن کاملEvaluation of the effect of dapagliflozin on cardiac repolarization: a thorough QT/QTc study
INTRODUCTION Dapagliflozin is a first-in-class sodium-glucose transporter 2 (SGLT2) inhibitor under investigation for the treatment of type 2 diabetes mellitus. A thorough QTc study was conducted, according to International Conference on Harmonization E14 guidelines, to characterize the effect of dapagliflozin on cardiac repolarization. METHODS The present study was a double-blind, four-perio...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Obesity Research
سال: 1997
ISSN: 1071-7323
DOI: 10.1002/j.1550-8528.1997.tb00573.x